By Rana S. Hoda MD FIAC, S A Hoda
This publication is meant as a pragmatic primer at the Pap attempt. utilizing daring textual content, tables, and highlighted components, this ebook bargains a simple textual content on Pap attempt basics so readers may well locate particular info without difficulty. This e-book starts off with a uncomplicated dictionary of phrases, ideas, and anatomy earlier than detailing such concerns because the Bethesda method, liquid-based and physiological cytology, reactive adjustments, human papillomavirus, and extraordinary squamous cells. The authors additionally talk about low-grade and high-grade squamous intra-epithelial lesions, invasive squamous carcinoma, endocervical and endometrial lesions, metastatic tumors, therapy-related alterations, and the most recent suggestions in screening and handling Pap tests.
This e-book is an extremely great tool for cytotechnologists and cytopathologists, in addition to these in education. Readers getting ready for varied talent and licensing examinations also will locate worthy details all through this volume.
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Extra info for Fundamentals of Pap Test Cytology
Same case as in Fig. 5 (H&E stain). Table 5 Decidual Cells vs Low-Grade Squamous Intra-Epithelial Lesions Features Cytoplasm Koilocytosis Nuclei Nucleolus History Decidual cells Abundant, pale and degenerative Absent Smooth contours Prominent, basophilic Helpful (pregnancy, postpartum) LSIL Mature Present with HPV "Raisinoid" with HPV Absent May not help Note: abundant pale cytoplasm and central round nucleus with prominent nucleoli differentiates decidual cells from LSIL. HPY, human papillomavirus; LSIL, low-grade squamous intra-epithelial lesion.
Liquid-Based Preparations 33 Table 2 General Cytological Features on Liquid-Based Preparations and Conventional Smear Features Background Clean RBCs Neutrophils Necrosis Cellularity Cell preservation Cell distribution Cell size Architecture Cytomorphology EC material Quantity Quality Artifacts Slide evaluation Reproducibility Ancillary studies ThinPrep SurePath Conventional smear Yes Reduced Reduced Clumped Adequate Good Uniform One plane Smaller Preserved Preserved Yes Reduced Reduced Clumped Adequate Good Uniform to uneven Different planes Smaller Preserved Preserved No Present/usually obscures Present/usually obscures Diffuse/usually obscures Adequate +/Uniform to uneven Larger Preserved Preserved Reduced Clumped None Easier (+) Possible Reduced Clumped None Easy to difficult (+) Possible Diffuse Usually +a Easy to difficult Usually not Usually not aAir-drying thick and obscured cell groups.
Squamocolumnar junctional mucosa (H&E stain). Table 3 Squamous Metaplasia vs SIL Cells Nucleus Cytoplasm Squamous metaplasia SIL Flattened Small